منابع مشابه
Personal viewpoint Epigenetics of inflammatory bowel disease
Understanding the causes and molecular mechanisms of Crohn’s disease and ulcerative colitis, the two forms of idiopathic chronic inflammatory bowel disease (IBD), is a major challenge in gastroenterology research. Significant eVort has been invested in uncovering genetic and environmental factors which may increase the risk of IBD, but progress has been slow, and no IBD specific factors have be...
متن کاملInflammatory Bowel Disease: Genetics, Epigenetics, and Pathogenesis
Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent research has suggested that genetic factors, environment, microbiota, and immune response are involved in the pathogenesis. Epidemiological evidence for a genetic contribution is defined: 15% of patients with Crohn...
متن کاملNeonatal Presentation of Unremitting Inflammatory Bowel Disease
Very-early-onset inflammatory bowel disease (VEO-IBD) has a distinct phenotype and should be considered a specific entity. VEO-IBD presents with very severe clinical pictures and is frequently known by an indeterminate colitis whose clinical remission is unmanageable. This study examines the case of a neonate with VEO-IBD, not responding to medical and surgical treatment. A 7-day-old Iranian fe...
متن کاملEffects of Probiotics and Prebiotics in Inflammatory Bowel Disease
Inflammatory bowel diseases (IBD) including most important forms; Crohn’s disease (CD) and ulcerative colitis (UC); are chronic diseases affecting the gastrointestinal tract with unclear etiology and pathology. The role of gut microbiota has recently been considered as major a factor, since altered microbiome or "dysbiosis" is a key player in the protracted course of inflammation in IBD. Howeve...
متن کاملinflammatory bowel disease
inflammatory bowel disease (ibd) is the term used for a group of diseases with yet unknown etiology, prevalence of which is increasing almost everywhere in the world. the disease was almost non-existent four decades ago in the east, including the middle-east, while now a days it is seen more and more. in addition to the increasing prevalence, our knowledge about its pathogenesis, clinical cours...
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ژورنال
عنوان ژورنال: Gut
سال: 2000
ISSN: 0017-5749
DOI: 10.1136/gut.47.2.302